Injectable Processing Skid
Propack Technologies: is a leading provider of Injectables Manufacturing Equipment for sterile solutions. Our injectable making machines can handle capacities from 5 L to 30,000 L, producing high-quality products such as vials, IV fluids, aerosols, ampoules, and LVP - SVP solutions. We customize our systems to meet the cGAMP and ASME BPE standards for aseptic manufacturing.
Our injectable processing systems include a full range of process vessels and their automation, with an optional SCADA package for enhanced control and monitoring. We also supply all the necessary peripherals, such as suction pumps, CIP/SIP systems, and the filling line interface with transfer pump.
Benefits of Injectable Processing Skid Manufacturing Plant
- 1Aseptic mixing & blending vessels designed as per ASME BPE / cGAMP / PED / USFDA
- 2Bottom mounted magnetic mixer as per requirements
- 3Skid customized & engineered as per process requirement
- 4Complete CIP / SIP able system with 100% drain
- 5In-house programming expertise to design customized recipe cycles
- 6Automation as per 21 CFR part 11
- 7Aseptic block valves are used to minimize dead zones.
We offer the following customizations according to client specific needs:
- Manufacturing vessel
- Holding Vessel
- Magnetic Mixers
- Sampling Valve
- Conductivity Sensor
- DO sensor
- pH Sensor
- Product Filter
- CIP - SIP of entire skid
A standard sterile aseptic manufacturing system comprises of two vessels although the systems might vary considerably according to each individual needs. Complete isolation from contamination is the main consideration in Injectables Manufacturing Equipment. Each vessel is therefore designed as per cGAMP and ASME BPE guidelines. The vessels can be customized as per the client needs to include magnetic mixers as per product needs. Various sensors like pH sensor, DO sensor, Conductivity sensor, Level sensor and charting devices can also be included into the injection manufacturing Skid as per needs.
The operations of centrifugal pump, pneumatically operated valves (in case of automated operation) and mixers is carried out through the main control panel. The panel is made out of SS304 grade material and consists of various safety lock systems like the Emergency stop and Mains supply indicators for safe work and extended component life. The vessels are connected to each other via interconnecting pipelines manufactured as per cGMP norms and connected with sealed tri clamp connection.
Features of Injectable Processing Skid Manufacturing Plant :
- Uniform ingredient dispersion
- No wall caking
- Entire plant operation by one operator and one helper
- Efficient heat transfer in the vessels
- Particle size reduction less than 5 microns
- Reduced batch processing time
- Reduced change over time
- Consistent product composition across different batches
- All contact parts made of SS316L and non-contact parts made of SS304 grade material
- Food grade silicone gaskets
- Vessel design as per ASME guidelines
- Torispherical, Hemispherical and Conical dish top customization availability
- Hydraulic lid lifting arrangement for occasional cleaning
- Static & Dynamic spray ball availability
- VFD for motor rpm controls
